ATXN7L1

Across TCGA patient cohorts, ATXN7L1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,152 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ATXN7L1-associated genes across cancer lineages are RNA5SP145, RNU6-1308P, and RNU6-762P. Each is linked with ATXN7L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATXN7L1-to-partner and partner-to-ATXN7L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN7L1 versus RNA5SP145 in UCEC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN7L1→partner) and Y-score (partner→ATXN7L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP145 →	+1.151	+1.290	.001	.002	3	2
UCEC	RNU6-1308P →	+1.821	+1.448	<.001	<.001	3	2
LUAD	RNU6-762P →	+0.695	+0.755	.001	.002	3	2
BRCA	ANKEF1 →	-1.486	-0.524	.009	.006	3	2
GBM	FAM209A →	+0.818	+1.796	.006	.003	3	2
GBM	TTLL4 →	+0.708	+1.261	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,152 associations by consensus.

ATXN7L1 vs RNA5SP145 — UCEC

Explore this scatter interactively →