ATXN7

Across TCGA patient cohorts, ATXN7 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,686 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ATXN7-associated proteins across cancer lineages are QRICH1, CGGBP1, and DCAF1. Each is linked with ATXN7 in more than 5 cancer types. Because this analysis shows association rather than direction, both ATXN7-to-partner and partner-to-ATXN7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN7 versus QRICH1 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN7→partner) and Y-score (partner→ATXN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	QRICH1 →	+0.210	+0.254	<.001	.001	3	5
HNSC	CGGBP1 →	+0.467	+0.562	<.001	<.001	3	5
LUAD	DCAF1 →	+0.240	+0.330	<.001	<.001	3	5
LSCC	ERO1A →	-0.548	-0.233	<.001	.001	2	6
OV	CLPX →	-0.256	-0.697	<.001	.001	3	4
PDAC	OXSR1 →	+0.192	+0.195	.006	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,686 associations by consensus.

ATXN7 vs QRICH1 — GBM

Explore this scatter interactively →