ATXN7

Across TCGA patient cohorts, ATXN7 protein abundance is significantly associated with the RNA expression of many other genes, with 4,682 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ATXN7-associated genes across cancer lineages are CPE, P3H1, and COPZ2. Each is linked with ATXN7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATXN7-to-partner and partner-to-ATXN7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN7 versus CPE in PDAC, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN7→partner) and Y-score (partner→ATXN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CPE →	-1.596	-0.712	<.001	<.001	3	3
BRCA	P3H1 →	-0.589	-0.286	<.001	.009	3	3
PDAC	COPZ2 →	-1.086	-0.652	<.001	<.001	3	3
PDAC	COLEC11 →	-1.116	-0.362	.004	.003	3	3
LSCC	RN7SKP240 →	-1.056	-0.279	<.001	<.001	3	3
LSCC	NBAT1 →	-0.879	-0.297	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,682 associations by consensus.

ATXN7 vs CPE — PDAC

Explore this scatter interactively →