ATXN2L

Across TCGA patient cohorts, ATXN2L RNA expression is significantly associated with the protein abundance of many other proteins, with 11,070 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATXN2L-associated proteins across cancer lineages are PRPF4B_S294, NUP54, and BOD1L1_S3029. Each is linked with ATXN2L in more than 4 cancer types. Because this analysis shows association rather than direction, both ATXN2L-to-partner and partner-to-ATXN2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN2L versus PRPF4B_S294 in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN2L→partner) and Y-score (partner→ATXN2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PRPF4B_S294 →	+0.748	+0.346	<.001	<.001	3	5
GBM	NUP54 →	+0.178	+0.379	.003	.001	3	4
BRCA	BOD1L1_S3029 →	+0.362	+0.468	.004	.004	3	4
PDAC	VTI1B →	-0.250	-0.306	.004	.006	3	4
CCRCC	CTNND1_T916 →	-0.893	-0.445	<.001	<.001	3	4
LUAD	CYSLTR1_S326 →	-0.973	-0.619	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,070 associations by consensus.

ATXN2L vs PRPF4B_S294 — PDAC

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