ATXN2L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATXN2L protein abundance is significantly associated with the protein abundance of many other proteins, with 27,391 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATXN2L-associated proteins across cancer lineages are RIF1_S782, SFPQ, and SRPK1_S51. Each is linked with ATXN2L in more than 8 cancer types. Because this analysis shows association rather than direction, both ATXN2L-to-partner and partner-to-ATXN2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN2L versus RIF1_S782 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN2L→partner) and Y-score (partner→ATXN2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARIF1_S782 →+0.818+0.218<.001<.00139
GBMSFPQ →+0.253+0.149<.001<.00139
PDACSRPK1_S51 →+0.638+0.201<.001<.00139
GBMSRRM2 →+0.264+0.175<.001<.00139
GBMTCERG1 →+0.287+0.145<.001<.00139
UCECUBAP2L →+0.259+0.188<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 27,391 associations by consensus.

ATXN2L vs RIF1_S782 — BRCA

Per-sample scatter of ATXN2L vs RIF1_S782 in BRCA (Pearson r = 0.42).

Explore this scatter interactively →

Exploration