ATXN2L

Across TCGA cell cohorts, ATXN2L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,336 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATXN2L-associated GO terms across cancer lineages are Regulation of chromatin organization, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Calcium-independent cell-matrix adhesion. Each is linked with ATXN2L in more than 13 cancer types. Because this analysis shows association rather than direction, both ATXN2L-to-partner and partner-to-ATXN2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by ATXN2L-low versus ATXN2L-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN2L→partner) and Y-score (partner→ATXN2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of chromatin organization →	+0.094	+0.691	<.001	<.001	3	14
SOFT_TISSUE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.134	+0.597	<.001	<.001	3	14
BONE	Calcium-independent cell-matrix adhesion →	+0.238	+0.725	<.001	<.001	3	13
STOMACH	Protein sumoylation →	+0.072	+0.605	.002	.002	3	13
BONE	Subtelomeric heterochromatin formation →	+0.165	+0.878	<.001	<.001	3	13
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.196	+0.798	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,336 associations by consensus.

Regulation of chromatin organization by ATXN2L expression — BREAST

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