ATXN2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ATXN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,340 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATXN2-associated GO terms across cancer lineages are Endosomal transport, Regulation of protein sumoylation, and Regulation of macroautophagy. Each is linked with ATXN2 in more than 15 cancer types. Because this analysis shows association rather than direction, both ATXN2-to-partner and partner-to-ATXN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN2→partner) and Y-score (partner→ATXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHEndosomal transport →+0.087+1.215<.001<.001316
LARGE_INTESTINERegulation of protein sumoylation →+0.125+0.801<.001<.001316
STOMACHRegulation of macroautophagy →+0.093+1.186<.001<.001314
STOMACHCytosolic transport →+0.084+1.288.001<.001314
BLOOD_LeukemiaNegative regulation of DNA-templated transcription initiation →+0.140+0.581<.001<.001314
STOMACHHeterochromatin formation →+0.082+1.041.003.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,340 associations by consensus.

Exploration