ATXN10

Across TCGA patient cohorts, ATXN10 protein abundance is significantly associated with the RNA expression of many other genes, with 11,980 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATXN10-associated genes across cancer lineages are TOMM22, MCAT, and XRCC6. Each is linked with ATXN10 in more than 8 cancer types. Because this analysis shows association rather than direction, both ATXN10-to-partner and partner-to-ATXN10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN10 versus TOMM22 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN10→partner) and Y-score (partner→ATXN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TOMM22 →	+0.804	+0.321	.002	<.001	3	9
HNSC	MCAT →	+0.659	+0.229	<.001	.001	3	9
HNSC	XRCC6 →	+0.742	+0.173	.007	.001	3	8
UCEC	SAMM50 →	+0.530	+0.194	.001	.002	2	9
HNSC	ST13 →	+0.643	+0.219	.006	.002	3	8
HNSC	NDUFA6 →	+0.586	+0.169	.007	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,980 associations by consensus.

ATXN10 vs TOMM22 — HNSC

Explore this scatter interactively →