ATXN10

Across TCGA patient cohorts, ATXN10 mutation is significantly associated with the RNA expression of many other genes, with 1,286 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATXN10-associated genes across cancer lineages are RN7SL134P, ATP6V1E1P2, and GAGE12H. Each is linked with ATXN10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATXN10-to-partner and partner-to-ATXN10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by ATXN10-low versus ATXN10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN10→partner) and Y-score (partner→ATXN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.094	+2.158	.002	.001	3	2
BLCA	ATP6V1E1P2 →	+0.161	+5.588	.003	.004	3	2
ESCA	GAGE12H →	+1.188	+5.681	<.001	.003	3	2
SKCM	SNRPGP17 →	+0.330	+4.052	<.001	.005	3	2
SKCM	NANOGNBP2 →	+0.123	+4.135	.001	.004	3	2
UCEC	RNU6-33P →	+0.367	+1.860	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,286 associations by consensus.

RN7SL134P by ATXN10 expression — UCEC

Explore this box plot interactively →