ATXN10

Across TCGA cell cohorts, ATXN10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,617 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATXN10-associated GO terms across cancer lineages are Aerobic respiration, DNA replication-dependent chromatin assembly, and Caveola assembly. Each is linked with ATXN10 in more than 7 cancer types. Because this analysis shows association rather than direction, both ATXN10-to-partner and partner-to-ATXN10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by ATXN10-low versus ATXN10-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN10→partner) and Y-score (partner→ATXN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Aerobic respiration →	+0.054	+0.612	.003	.003	3	8
LARGE_INTESTINE	DNA replication-dependent chromatin assembly →	+0.101	+1.180	<.001	<.001	3	8
BREAST	Caveola assembly →	+0.253	+0.952	<.001	<.001	3	7
LARGE_INTESTINE	Caveolin-mediated endocytosis →	+0.204	+0.970	<.001	<.001	3	7
BREAST	Regulation of Golgi inheritance →	+0.145	+0.943	<.001	<.001	3	7
LUNG_SCLC	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway →	+0.069	+0.458	.009	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,617 associations by consensus.

Aerobic respiration by ATXN10 expression — PANCREAS

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