ATRNL1

Across TCGA patient cohorts, ATRNL1 mutation is significantly associated with the RNA expression of many other genes, with 3,745 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATRNL1-associated genes across cancer lineages are PSMC3IP, TACC3, and FEN1. Each is linked with ATRNL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ATRNL1-to-partner and partner-to-ATRNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMC3IP grouped by ATRNL1-low versus ATRNL1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRNL1→partner) and Y-score (partner→ATRNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PSMC3IP →	+0.489	+3.195	.005	.009	3	5
COAD	TACC3 →	+0.490	+3.342	.009	.005	3	5
UCEC	FEN1 →	+0.560	+1.472	<.001	<.001	3	5
LUAD	E2F1 →	+0.633	+2.514	<.001	<.001	2	5
UCEC	CSTF2 →	+0.277	+1.451	.007	<.001	3	4
UCEC	OIP5 →	+0.645	+1.758	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,745 associations by consensus.

PSMC3IP by ATRNL1 expression — STAD

Explore this box plot interactively →