ATRNL1

Across TCGA patient cohorts, ATRNL1 mutation is significantly associated with the total protein of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATRNL1-associated genes across cancer lineages are Cyclin-B1, 4E-BP1, and eIF4E. Each is linked with ATRNL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATRNL1-to-partner and partner-to-ATRNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by ATRNL1-low versus ATRNL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRNL1→partner) and Y-score (partner→ATRNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.498	+1.765	.001	.013	3	4
STAD	4E-BP1 →	+0.341	+3.321	.015	.010	3	4
UCEC	eIF4E →	+0.125	+1.820	.034	.014	3	4
SKCM	GAPDH →	+0.522	+1.662	.011	.011	3	3
LUAD	JNK2 →	-0.142	-1.999	.014	.029	3	3
LUAD	Cyclin-D1 →	-0.141	-3.000	.018	.034	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Cyclin-B1 by ATRNL1 expression — UCEC

Explore this box plot interactively →