ATRIP

Across TCGA patient cohorts, ATRIP protein abundance is significantly associated with the RNA expression of many other genes, with 3,561 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATRIP-associated genes across cancer lineages are TMPRSS11F, CCDC58, and CDC6. Each is linked with ATRIP in more than 2 cancer types. Because this analysis shows association rather than direction, both ATRIP-to-partner and partner-to-ATRIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATRIP versus TMPRSS11F in GBM, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRIP→partner) and Y-score (partner→ATRIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMPRSS11F →	-0.541	-0.295	.001	.002	3	3
LSCC	CCDC58 →	+0.630	+0.244	<.001	.002	3	3
UCEC	CDC6 →	+0.671	+0.199	.007	.009	3	3
OV	CIB2 →	-0.841	-0.601	<.001	<.001	3	2
OV	S100A8 →	+2.593	+0.929	<.001	<.001	3	2
LUAD	FSD2 →	-0.144	-0.175	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,561 associations by consensus.

ATRIP vs TMPRSS11F — GBM

Explore this scatter interactively →