ATRIP

Across TCGA patient cohorts, ATRIP mutation is significantly associated with the RNA expression of many other genes, with 2,010 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATRIP-associated genes across cancer lineages are MIR3661, RNA5SP176, and LINC01442. Each is linked with ATRIP in more than 2 cancer types. Because this analysis shows association rather than direction, both ATRIP-to-partner and partner-to-ATRIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3661 grouped by ATRIP-low versus ATRIP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRIP→partner) and Y-score (partner→ATRIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3661 →	+0.616	+2.114	<.001	<.001	3	3
BLCA	RNA5SP176 →	+0.338	+7.640	<.001	.009	3	2
CESC	LINC01442 →	+0.021	+5.669	<.001	.003	3	2
LUAD	M6PRP1 →	+0.037	+4.197	<.001	.009	3	2
BRCA	ST6GALNAC2P1 →	+0.044	+5.786	.008	.001	3	2
UCEC	HSBP1P2 →	+0.439	+1.956	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,010 associations by consensus.

MIR3661 by ATRIP expression — UCEC

Explore this box plot interactively →