ATRAID

Across TCGA patient cohorts, ATRAID RNA expression is significantly associated with the protein abundance of many other proteins, with 11,634 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATRAID-associated proteins across cancer lineages are UBE2J1, WDFY4, and ICAM3. Each is linked with ATRAID in more than 4 cancer types. Because this analysis shows association rather than direction, both ATRAID-to-partner and partner-to-ATRAID results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATRAID versus UBE2J1 in LSCC, with a Pearson correlation of -0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRAID→partner) and Y-score (partner→ATRAID) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBE2J1 →	-0.510	-0.359	<.001	<.001	3	4
HNSC	WDFY4 →	-0.426	-0.896	.001	.007	3	4
UCEC	ICAM3 →	-0.722	-0.633	<.001	.002	2	5
LSCC	TENT5C →	-0.613	-0.424	<.001	<.001	3	4
LSCC	RCSD1 →	-0.436	-0.358	<.001	<.001	3	4
BRCA	SEPTIN10 →	+0.396	+0.468	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,634 associations by consensus.

ATRAID vs UBE2J1 — LSCC

Explore this scatter interactively →