ATRAID

Across TCGA patient cohorts, ATRAID protein abundance is significantly associated with the RNA expression of many other genes, with 8,437 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ATRAID-associated genes across cancer lineages are PRSS3, YKT6, and PACRG. Each is linked with ATRAID in more than 2 cancer types. Because this analysis shows association rather than direction, both ATRAID-to-partner and partner-to-ATRAID results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATRAID versus PRSS3 in PDAC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRAID→partner) and Y-score (partner→ATRAID) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PRSS3 →	-1.863	-1.019	.003	<.001	3	3
PDAC	YKT6 →	+0.350	+0.609	.001	.004	3	3
PDAC	PACRG →	-0.365	-0.611	.005	<.001	3	3
CCRCC	C7 →	-2.213	-0.273	<.001	<.001	3	3
GBM	PAIP2B →	-1.199	-0.246	<.001	.001	3	3
HNSC	IAH1 →	+0.405	+0.311	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,437 associations by consensus.

ATRAID vs PRSS3 — PDAC

Explore this scatter interactively →