ATR

Across TCGA patient cohorts, ATR protein abundance is significantly associated with the protein abundance of many other proteins, with 18,465 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATR-associated proteins across cancer lineages are NCAPG, ATR_S435, and CZIB. Each is linked with ATR in more than 6 cancer types. Because this analysis shows association rather than direction, both ATR-to-partner and partner-to-ATR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATR versus NCAPG in LUAD, with a Pearson correlation of 0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATR→partner) and Y-score (partner→ATR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NCAPG →	+0.519	+0.264	<.001	<.001	3	7
COAD	ATR_S435 →	+0.893	+0.821	<.001	<.001	3	6
HNSC	CZIB →	-0.337	-0.320	<.001	<.001	3	6
HNSC	DCTN4 →	-0.236	-0.242	<.001	<.001	3	6
CCRCC	GNB1 →	-0.416	-0.366	<.001	<.001	3	6
LSCC	CHAF1B →	+0.618	+0.304	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,465 associations by consensus.

ATR vs NCAPG — LUAD

Explore this scatter interactively →