ATPAF2

Across TCGA patient cohorts, ATPAF2 mutation is significantly associated with the RNA expression of many other genes, with 365 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATPAF2-associated genes across cancer lineages are OR4C49P, DPPA5P1, and MRPL32P1. Each is linked with ATPAF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATPAF2-to-partner and partner-to-ATPAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4C49P grouped by ATPAF2-low versus ATPAF2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATPAF2→partner) and Y-score (partner→ATPAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR4C49P →	+0.086	+5.182	<.001	.007	3	2
BLCA	DPPA5P1 →	+0.158	+3.719	.001	.008	3	2
UCEC	MRPL32P1 →	+0.181	+3.109	.001	.007	3	2
UCEC	SNORD111B →	+0.461	+3.031	<.001	.003	3	2
UCEC	RPL31P47 →	+0.328	+2.899	<.001	.002	3	2
UCEC	MIR5188 →	+0.867	+3.235	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 365 associations by consensus.

OR4C49P by ATPAF2 expression — HNSC

Explore this box plot interactively →