ATPAF2

Across TCGA cell cohorts, ATPAF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,724 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATPAF2-associated GO terms across cancer lineages are Glycine biosynthetic process, DNA topological change, and Positive regulation of DNA metabolic process. Each is linked with ATPAF2 in more than 18 cancer types. Because this analysis shows association rather than direction, both ATPAF2-to-partner and partner-to-ATPAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycine biosynthetic process grouped by ATPAF2-low versus ATPAF2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATPAF2→partner) and Y-score (partner→ATPAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Glycine biosynthetic process →	+0.208	+0.696	<.001	<.001	3	19
LUNG_SCLC	DNA topological change →	+0.151	+0.728	<.001	.001	3	13
BLOOD_Lymphoma	Positive regulation of DNA metabolic process →	+0.052	+0.726	<.001	<.001	3	12
BREAST	5-phosphoribose 1-diphosphate metabolic process →	+0.127	+0.808	.001	<.001	3	11
BREAST	5-phosphoribose 1-diphosphate biosynthetic process →	+0.127	+0.808	.001	<.001	3	11
BONE	DTMP biosynthetic process →	+0.215	+0.770	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,724 associations by consensus.

Glycine biosynthetic process by ATPAF2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →