ATPAF1

Across TCGA patient cohorts, ATPAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,028 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATPAF1-associated genes across cancer lineages are GOT1, ALDH5A1, and SPARC. Each is linked with ATPAF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ATPAF1-to-partner and partner-to-ATPAF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATPAF1 versus GOT1 in HNSC, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATPAF1→partner) and Y-score (partner→ATPAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GOT1 →	+0.665	+0.229	.003	.001	3	5
HNSC	ALDH5A1 →	+0.838	+0.344	<.001	<.001	3	4
COAD	SPARC →	-0.951	-0.297	.007	.003	3	4
LSCC	NDUFB5 →	+0.650	+0.358	<.001	<.001	3	4
LSCC	SELENOI →	+0.853	+0.263	<.001	<.001	3	4
COAD	EMP3 →	-0.739	-0.387	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,028 associations by consensus.

ATPAF1 vs GOT1 — HNSC

Explore this scatter interactively →