ATPAF1

Across TCGA patient cohorts, ATPAF1 mutation is significantly associated with the RNA expression of many other genes, with 1,180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATPAF1-associated genes across cancer lineages are ELOCP5, RNU6-302P, and SNORA10B. Each is linked with ATPAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATPAF1-to-partner and partner-to-ATPAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOCP5 grouped by ATPAF1-low versus ATPAF1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATPAF1→partner) and Y-score (partner→ATPAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ELOCP5 →	+0.096	+8.057	<.001	.005	3	2
UCEC	RNU6-302P →	+0.358	+1.848	.002	.009	3	2
BRCA	SNORA10B →	+0.253	+5.441	.001	.005	3	2
BRCA	RNA5SP365 →	+0.387	+5.122	<.001	.008	3	1
BRCA	LINC02824 →	+0.079	+5.441	.002	.005	3	1
BRCA	DBF4P3 →	+0.114	+5.175	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,180 associations by consensus.

ELOCP5 by ATPAF1 expression — BRCA

Explore this box plot interactively →