ATPAF1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ATPAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,156 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATPAF1-associated GO terms across cancer lineages are Progesterone biosynthetic process, Mitochondrial respiratory chain complex assembly, and Regulation of leukocyte migration. Each is linked with ATPAF1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ATPAF1-to-partner and partner-to-ATPAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Progesterone biosynthetic process grouped by ATPAF1-low versus ATPAF1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATPAF1→partner) and Y-score (partner→ATPAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCProgesterone biosynthetic process →+0.255+0.701.001<.00139
BLOOD_LeukemiaMitochondrial respiratory chain complex assembly →+0.040+0.720<.001<.00139
LARGE_INTESTINERegulation of leukocyte migration →-0.045-0.537.003<.00139
UPPER_AERODIGESTIVE_TRACTRegulation of centriole replication →+0.102+1.039<.001<.00138
OESOPHAGUSQuinone biosynthetic process →+0.096+0.977<.001<.00138
UPPER_AERODIGESTIVE_TRACTCell junction assembly →-0.076-1.152<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,156 associations by consensus.

Progesterone biosynthetic process by ATPAF1 expression — LUNG_SCLC

Box plot of Progesterone biosynthetic process in ATPAF1-low vs ATPAF1-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration