ATP9B

Across TCGA cell cohorts, ATP9B mutation is significantly associated with the RNA expression of many other genes, with 747 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP9B-associated genes across cancer lineages are C12orf57, CD300H, and CST9L. Each is linked with ATP9B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP9B-to-partner and partner-to-ATP9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C12orf57 grouped by ATP9B-low versus ATP9B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP9B→partner) and Y-score (partner→ATP9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C12orf57 →	+1.128	+3.489	.001	.001	3	2
OVARY	CD300H →	+0.065	+5.196	<.001	.005	3	2
LUNG_SCLC	CST9L →	+0.045	+4.643	<.001	.004	3	2
BLOOD_Lymphoma	RIPPLY1 →	+0.038	+4.191	<.001	.007	3	2
UPPER_AERODIGESTIVE_TRACT	MTRNR2L6 →	+0.173	+5.357	<.001	.003	3	2
LARGE_INTESTINE	RPL11 →	+0.352	+3.321	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 747 associations by consensus.

C12orf57 by ATP9B expression — BLOOD_Leukemia

Explore this box plot interactively →