ATP9A

Across TCGA cell cohorts, ATP9A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,015 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ATP9A-associated GO terms across cancer lineages are Negative regulation of exosomal secretion, Golgi to endosome transport, and Post-Golgi vesicle-mediated transport. Each is linked with ATP9A in more than 13 cancer types. Because this analysis shows association rather than direction, both ATP9A-to-partner and partner-to-ATP9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of exosomal secretion grouped by ATP9A-low versus ATP9A-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP9A→partner) and Y-score (partner→ATP9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of exosomal secretion →	+0.274	+1.739	<.001	<.001	3	14
STOMACH	Golgi to endosome transport →	+0.135	+2.260	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Post-Golgi vesicle-mediated transport →	+0.067	+0.994	.003	.008	3	12
SKIN	Positive regulation of protein catabolic process →	+0.048	+1.420	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.066	+1.016	.003	.004	3	11
BONE	Regulation of retrograde transport, endosome to Golgi →	+0.133	+1.546	.004	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,015 associations by consensus.

Negative regulation of exosomal secretion by ATP9A expression — URINARY_TRACT

Explore this box plot interactively →