ATP9A

Across TCGA cell cohorts, ATP9A mutation is significantly associated with the RNA expression of many other genes, with 1,002 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP9A-associated genes across cancer lineages are RCBTB1, PIGK, and ENPP4. Each is linked with ATP9A in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP9A-to-partner and partner-to-ATP9A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RCBTB1 grouped by ATP9A-low versus ATP9A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP9A→partner) and Y-score (partner→ATP9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RCBTB1 →	+0.574	+2.502	.004	.005	3	2
LARGE_INTESTINE	PIGK →	+0.535	+2.502	.003	.005	3	2
LARGE_INTESTINE	ENPP4 →	+0.791	+3.321	<.001	.003	3	2
LARGE_INTESTINE	FBXW10 →	+0.205	+3.800	<.001	<.001	3	2
LUNG_NSCLC_LUAD	TAAR8 →	+0.013	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	PNLIPRP3 →	+1.020	+4.442	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,002 associations by consensus.

RCBTB1 by ATP9A expression — LARGE_INTESTINE

Explore this box plot interactively →