ATP8B5P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ATP8B5P Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ATP8B5P data layer compared with 25 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ATP8B5P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ATP8B5P expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BLCA and UCEC are the cancer types where ATP8B5P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSMedianAll0.2160.710.01330view →
UCECDFSMedianAll0.9290.620.0342view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ATP8B5P–BLCA (OS)

Kaplan–Meier survival curve for ATP8B5P mutant vs wild-type samples in BLCA.

Open the BLCA breakdown →

Exploration