ATP7B

Across TCGA pan-cancer cohorts, ATP7B mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ATP7B data layer compared with 24 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ATP7B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP7B expression acts as an unfavorable survival marker.

CCRCC are the cancer types where ATP7B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.322	1.000	.001	32	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ATP7B–CCRCC (DFS)

Open the CCRCC breakdown →