Across TCGA patient cohorts, ATP6V1G2 mutation is significantly associated with the RNA expression of many other genes, with 217 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1G2-associated genes across cancer lineages are LAMTOR1, NGLY1, and BOLA3. Each is linked with ATP6V1G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1G2-to-partner and partner-to-ATP6V1G2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1G2→partner) and Y-score (partner→ATP6V1G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LAMTOR1 →	+0.415	+3.470	.009	.003	3	1
UCEC	NGLY1 →	+0.481	+3.491	.009	.002	3	1
UCEC	BOLA3 →	+0.506	+3.218	.005	.009	3	1
UCEC	AIMP1 →	+0.551	+3.480	.002	.002	3	1
UCEC	TRUB2 →	+0.412	+3.234	.008	.009	3	1
UCEC	FBXO22 →	+0.546	+3.212	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 217 associations by consensus.

Exploration

ATP6V1G2 survival (RNA) · tumor vs normal (RNA) · all ATP6V1G2 data types