Across TCGA patient cohorts, ATP6V1G2 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1G2-associated genes across cancer lineages are IGFBP2, MEK1, and mTOR. Each is linked with ATP6V1G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1G2-to-partner and partner-to-ATP6V1G2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1G2→partner) and Y-score (partner→ATP6V1G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.965	-3.459	.003	.005	3	1
UCEC	MEK1 →	+0.461	+2.321	.012	.035	3	1
UCEC	mTOR →	-0.204	-2.321	.011	.035	3	1
UCEC	p62 Lck ligand →	+0.372	+3.009	.023	.019	3	1
UCEC	Tuberin →	+0.399	+2.321	.003	.035	3	1
UCEC	Caspase-8 →	-0.253	-2.973	.045	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

ATP6V1G2 survival (RNA) · tumor vs normal (RNA) · all ATP6V1G2 data types