ATP6V1G1

Across TCGA pan-cancer cohorts, ATP6V1G1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ATP6V1G1 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ATP6V1G1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ATP6V1G1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and PDAC are the cancer types where ATP6V1G1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	1.000	0.433	.007	36	view →
CCRCC	DFS	Tertile	II,III,IV	0.909	0.517	.008	29	view →
PDAC	OS	Tertile	III,IV	0.229	0.613	.006	18	view →
HNSC	DFS	Quartile	III,IV	0.901	0.631	.015	17	view →
LUAD	OS	Quartile	All	0.715	0.902	.008	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ATP6V1G1–UCEC (OS)

Open the UCEC breakdown →