ATP6V1G1

Across TCGA patient cohorts, ATP6V1G1 mutation is significantly associated with the RNA expression of many other genes, with 249 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1G1-associated genes across cancer lineages are CLN8, CCDC196, and GTF2E2. Each is linked with ATP6V1G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1G1-to-partner and partner-to-ATP6V1G1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLN8 grouped by ATP6V1G1-low versus ATP6V1G1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1G1→partner) and Y-score (partner→ATP6V1G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CLN8 →	+0.697	+3.343	<.001	.005	3	1
UCEC	CCDC196 →	+0.191	+2.423	.001	.007	3	1
UCEC	GTF2E2 →	+0.618	+3.332	.001	.005	3	1
UCEC	MRPL42 →	+0.536	+3.354	.007	.005	3	1
UCEC	RNU6-1082P →	+0.237	+3.136	<.001	.007	3	1
UCEC	C7orf66 →	+0.337	+2.408	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 249 associations by consensus.

CLN8 by ATP6V1G1 expression — UCEC

Explore this box plot interactively →