ATP6V1G1

Across TCGA patient cohorts, ATP6V1G1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1G1-associated genes across cancer lineages are A-Raf_pS299, FoxM1, and FOXO3a_pS318_S321. Each is linked with ATP6V1G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1G1-to-partner and partner-to-ATP6V1G1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by ATP6V1G1-low versus ATP6V1G1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1G1→partner) and Y-score (partner→ATP6V1G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.187	-3.000	.006	.037	3	1
UCEC	FoxM1 →	+0.488	+3.000	.001	.037	3	1
UCEC	FOXO3a_pS318_S321 →	-0.183	-3.000	.011	.037	3	1
UCEC	p27 →	-0.267	-3.000	.034	.037	3	1
UCEC	Dvl3 →	+0.341	+3.000	.001	.036	3	1
UCEC	ARID1A →	-0.224	-2.992	.033	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

A-Raf_pS299 by ATP6V1G1 expression — UCEC

Explore this box plot interactively →