ATP6V1E2

Across TCGA patient cohorts, ATP6V1E2 protein abundance is significantly associated with the RNA expression of many other genes, with 532 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATP6V1E2-associated genes across cancer lineages are CLEC11A, GPRC5D, and LAMP5. Each is linked with ATP6V1E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1E2-to-partner and partner-to-ATP6V1E2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1E2 versus CLEC11A in GBM, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1E2→partner) and Y-score (partner→ATP6V1E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CLEC11A →	+1.493	+0.713	.004	.008	3	1
GBM	GPRC5D →	+0.911	+0.826	<.001	.006	3	1
GBM	LAMP5 →	-2.719	-0.544	.002	.004	3	1
GBM	MACF1 →	-0.429	-0.706	.006	.009	3	1
GBM	NDUFA5 →	-0.950	-0.713	.001	.008	3	1
GBM	SUCLA2 →	-0.679	-0.713	.008	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 532 associations by consensus.

ATP6V1E2 vs CLEC11A — GBM

Explore this scatter interactively →