ATP6V1E2

Across TCGA patient cohorts, ATP6V1E2 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ATP6V1E2-associated genes across cancer lineages are RAD51, TAZ, and SCD. Each is linked with ATP6V1E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1E2-to-partner and partner-to-ATP6V1E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by ATP6V1E2-low versus ATP6V1E2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1E2→partner) and Y-score (partner→ATP6V1E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51 →	+0.154	+3.169	.045	.020	3	1
SKCM	TAZ →	+0.164	+3.012	.047	.018	3	1
SKCM	SCD →	-0.168	-3.321	.027	.010	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

RAD51 by ATP6V1E2 expression — UCEC

Explore this box plot interactively →