ATP6V1E2

Across TCGA cell cohorts, ATP6V1E2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,349 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP6V1E2-associated GO terms across cancer lineages are Potassium ion import across plasma membrane, Aminoacyl-tRNA metabolism involved in translational fidelity, and Transport along microtubule. Each is linked with ATP6V1E2 in more than 10 cancer types. Because this analysis shows association rather than direction, both ATP6V1E2-to-partner and partner-to-ATP6V1E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Potassium ion import across plasma membrane grouped by ATP6V1E2-low versus ATP6V1E2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1E2→partner) and Y-score (partner→ATP6V1E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Potassium ion import across plasma membrane →	-0.180	-0.943	.002	<.001	3	11
SOFT_TISSUE	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.092	+0.745	.005	.004	3	10
LUNG_NSCLC_LUSC	Transport along microtubule →	+0.053	+1.084	.002	.002	2	11
LARGE_INTESTINE	Mitochondrial DNA metabolic process →	+0.101	+0.997	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.061	+0.713	.004	.001	3	10
BLOOD_Lymphoma	Sex-chromosome dosage compensation →	+0.083	+0.647	.001	.005	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,349 associations by consensus.

Potassium ion import across plasma membrane by ATP6V1E2 expression — PANCREAS

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