ATP6V1E1

Across TCGA patient cohorts, ATP6V1E1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,482 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP6V1E1-associated genes across cancer lineages are ATP6V1B2, FGD2, and CTSB. Each is linked with ATP6V1E1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ATP6V1E1-to-partner and partner-to-ATP6V1E1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1E1 versus ATP6V1B2 in COAD, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1E1→partner) and Y-score (partner→ATP6V1E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ATP6V1B2 →	+0.596	+0.267	<.001	<.001	3	9
LSCC	FGD2 →	+0.663	+0.199	<.001	<.001	3	6
COAD	CTSB →	+0.630	+0.194	<.001	<.001	3	6
COAD	TNFRSF10A →	+0.611	+0.238	<.001	<.001	3	5
LSCC	SIGLEC9 →	+0.703	+0.298	<.001	<.001	3	5
COAD	CHMP7 →	+0.530	+0.240	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,482 associations by consensus.

ATP6V1E1 vs ATP6V1B2 — COAD

Explore this scatter interactively →