ATP6V1D

Across TCGA pan-cancer cohorts, ATP6V1D mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ATP6V1D data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ATP6V1D mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP6V1D expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

COAD, HNSC, and CCRCC are the cancer types where ATP6V1D mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.910	1.000	.011	90	view →
HNSC	OS	Tertile	All	1.000	0.930	.020	20	view →
CCRCC	DFS	Tertile	III,IV	0.810	0.454	.015	16	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	15	view →
LUAD	OS	Tertile	All	0.444	0.881	.002	14	view →
LSCC	OS	Median	All	0.793	1.000	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ATP6V1D–COAD (DFS)

Open the COAD breakdown →