ATP6V1D

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP6V1D mutation is significantly associated with the RNA expression of many other genes, with 828 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1D-associated genes across cancer lineages are MIR3928, TTTY7B, and RNU6-933P. Each is linked with ATP6V1D in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1D-to-partner and partner-to-ATP6V1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3928 grouped by ATP6V1D-low versus ATP6V1D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1D→partner) and Y-score (partner→ATP6V1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR3928 →+0.396+2.664<.001.00232
BRCATTTY7B →+0.016+7.471<.001.00832
UCECRNU6-933P →+0.553+2.547<.001<.00132
BRCAMIR6853 →+0.242+8.057<.001.00531
BRCAMIR7159 →+0.476+5.317<.001.00631
BRCAMIR6894 →+0.541+5.506<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 828 associations by consensus.

MIR3928 by ATP6V1D expression — UCEC

Box plot of MIR3928 in ATP6V1D-low vs ATP6V1D-high samples in UCEC.

Explore this box plot interactively →

Exploration