ATP6V1C1

Across TCGA patient cohorts, ATP6V1C1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,160 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ATP6V1C1-associated genes across cancer lineages are HAVCR2, SLC6A12, and SLC31A2. Each is linked with ATP6V1C1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ATP6V1C1-to-partner and partner-to-ATP6V1C1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1C1 versus HAVCR2 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1C1→partner) and Y-score (partner→ATP6V1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HAVCR2 →	+0.985	+0.294	.002	.001	3	6
UCEC	SLC6A12 →	+0.861	+0.219	<.001	<.001	3	5
GBM	SLC31A2 →	+0.797	+0.444	<.001	<.001	3	5
LUAD	ATP6V1B2 →	+0.512	+0.233	<.001	<.001	2	6
LSCC	CLEC7A →	+0.760	+0.157	.001	.001	3	5
UCEC	LILRB4 →	+1.172	+0.298	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,160 associations by consensus.

ATP6V1C1 vs HAVCR2 — UCEC

Explore this scatter interactively →