ATP6V1C1

Across TCGA patient cohorts, ATP6V1C1 mutation is significantly associated with the RNA expression of many other genes, with 649 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1C1-associated genes across cancer lineages are RNU6-1040P, RPS29P26, and LINC01810. Each is linked with ATP6V1C1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1C1-to-partner and partner-to-ATP6V1C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1040P grouped by ATP6V1C1-low versus ATP6V1C1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1C1→partner) and Y-score (partner→ATP6V1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1040P →	+0.497	+7.930	<.001	.008	3	2
LUAD	RPS29P26 →	+0.348	+7.930	<.001	.008	3	2
HNSC	LINC01810 →	+0.084	+7.954	<.001	.008	3	2
STAD	RNA5SP391 →	+0.337	+5.026	.005	.009	3	2
STAD	RNA5SP176 →	+0.946	+5.463	<.001	.005	3	2
LUSC	RNU6-1241P →	+0.299	+4.733	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 649 associations by consensus.

RNU6-1040P by ATP6V1C1 expression — LUAD

Explore this box plot interactively →