ATP6V1C1

Across TCGA cell cohorts, ATP6V1C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,558 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATP6V1C1-associated GO terms across cancer lineages are Synaptic vesicle lumen acidification, Blastocyst growth, and Vesicle-mediated transport between endosomal compartments. Each is linked with ATP6V1C1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ATP6V1C1-to-partner and partner-to-ATP6V1C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic vesicle lumen acidification grouped by ATP6V1C1-low versus ATP6V1C1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1C1→partner) and Y-score (partner→ATP6V1C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Synaptic vesicle lumen acidification →	+0.152	+0.761	<.001	<.001	3	14
PANCREAS	Blastocyst growth →	+0.189	+0.880	<.001	<.001	3	12
BLOOD_Myeloma	Vesicle-mediated transport between endosomal compartments →	+0.056	+1.576	.006	<.001	3	12
BLOOD_Myeloma	Early endosome to late endosome transport →	+0.056	+1.576	.006	<.001	3	12
KIDNEY	Synaptic vesicle maturation →	+0.149	+1.133	<.001	<.001	3	9
STOMACH	Endosomal transport →	+0.069	+1.098	.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,558 associations by consensus.

Synaptic vesicle lumen acidification by ATP6V1C1 expression — SOFT_TISSUE

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