ATP6V1B2

Across TCGA patient cohorts, ATP6V1B2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,637 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP6V1B2-associated genes across cancer lineages are TMEM97, LILRB4, and TNFRSF10A. Each is linked with ATP6V1B2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ATP6V1B2-to-partner and partner-to-ATP6V1B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1B2 versus TMEM97 in LSCC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1B2→partner) and Y-score (partner→ATP6V1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMEM97 →	-1.112	-0.258	<.001	<.001	3	6
COAD	LILRB4 →	+1.105	+0.251	<.001	<.001	3	6
COAD	TNFRSF10A →	+0.653	+0.221	<.001	<.001	3	5
OV	ABI3 →	+0.735	+0.178	<.001	<.001	3	5
OV	PIK3AP1 →	+0.939	+0.253	.001	.002	3	5
OV	FCER1G →	+1.149	+0.321	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,637 associations by consensus.

ATP6V1B2 vs TMEM97 — LSCC

Explore this scatter interactively →