ATP6V1B2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP6V1B2 mutation is significantly associated with the RNA expression of many other genes, with 1,679 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1B2-associated genes across cancer lineages are LINC01072, RNA5SP412, and IGKV2-36. Each is linked with ATP6V1B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP6V1B2-to-partner and partner-to-ATP6V1B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by ATP6V1B2-low versus ATP6V1B2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1B2→partner) and Y-score (partner→ATP6V1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADLINC01072 →+0.306+5.516<.001.00433
UCECRNA5SP412 →+0.522+2.137<.001<.00133
LGGIGKV2-36 →+0.184+7.977<.001.00732
BRCARN7SKP221 →+0.065+7.471<.001.00832
BRCATRDD1 →+0.910+8.057<.001.00532
UCECRNA5SP411 →+0.971+1.808<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,679 associations by consensus.

LINC01072 by ATP6V1B2 expression — COAD

Box plot of LINC01072 in ATP6V1B2-low vs ATP6V1B2-high samples in COAD.

Explore this box plot interactively →

Exploration