ATP6V1B2

Across TCGA cell cohorts, ATP6V1B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,184 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ATP6V1B2-associated GO terms across cancer lineages are Synaptic vesicle lumen acidification, Regulation of regulatory ncRNA-mediated heterochromatin formation, and Negative regulation of regulatory ncRNA-mediated heterochromatin formation. Each is linked with ATP6V1B2 in more than 16 cancer types. Because this analysis shows association rather than direction, both ATP6V1B2-to-partner and partner-to-ATP6V1B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic vesicle lumen acidification grouped by ATP6V1B2-low versus ATP6V1B2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1B2→partner) and Y-score (partner→ATP6V1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Synaptic vesicle lumen acidification →	+0.141	+0.856	.001	<.001	2	17
LIVER	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.142	+0.921	.001	.005	2	14
LIVER	Negative regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.142	+0.921	.001	.005	2	14
STOMACH	Positive regulation of telomere capping →	+0.110	+0.915	<.001	.001	3	12
BLOOD_Myeloma	Negative regulation of heterochromatin organization →	+0.122	+1.490	<.001	<.001	3	11
OESOPHAGUS	Negative regulation of chromatin organization →	+0.118	+0.629	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,184 associations by consensus.

Synaptic vesicle lumen acidification by ATP6V1B2 expression — SOFT_TISSUE

Explore this box plot interactively →