ATP6V1B1

Across TCGA patient cohorts, ATP6V1B1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,230 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ATP6V1B1-associated genes across cancer lineages are LYPD6B, LDLRAD1, and PLAAT2. Each is linked with ATP6V1B1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATP6V1B1-to-partner and partner-to-ATP6V1B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1B1 versus LYPD6B in UCEC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1B1→partner) and Y-score (partner→ATP6V1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LYPD6B →	+1.852	+0.881	<.001	<.001	3	4
LUAD	LDLRAD1 →	+1.363	+0.914	<.001	<.001	3	4
OV	PLAAT2 →	+1.084	+0.495	<.001	.001	3	3
OV	RASSF4 →	-0.649	-0.799	.008	.001	3	3
UCEC	RASAL1 →	+1.018	+0.449	.003	.006	3	3
OV	MMEL1 →	+0.784	+0.716	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,230 associations by consensus.

ATP6V1B1 vs LYPD6B — UCEC

Explore this scatter interactively →