ATP6V0E2

Across TCGA patient cohorts, ATP6V0E2 mutation is significantly associated with the RNA expression of many other genes, with 89 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ATP6V0E2-associated genes across cancer lineages are RNU1-62P, ATP5F1AP7, and RNU6-1169P. Each is linked with ATP6V0E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0E2-to-partner and partner-to-ATP6V0E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-62P grouped by ATP6V0E2-low versus ATP6V0E2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0E2→partner) and Y-score (partner→ATP6V0E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-62P →	+0.250	+4.539	<.001	.008	3	2
READ	ATP5F1AP7 →	+0.094	+5.421	<.001	.005	3	2
SKCM	RNU6-1169P →	+0.569	+5.362	<.001	.005	3	2
CESC	TIMM9P1 →	+0.199	+4.320	.001	.007	3	1
CESC	RPS27P12 →	+0.168	+4.969	<.001	.004	3	1
CESC	RN7SL314P →	+0.129	+5.569	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

RNU1-62P by ATP6V0E2 expression — CESC

Explore this box plot interactively →