ATP6V0E2

Across TCGA cell cohorts, ATP6V0E2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,025 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ATP6V0E2-associated GO terms across cancer lineages are ATP biosynthetic process, Purine nucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with ATP6V0E2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ATP6V0E2-to-partner and partner-to-ATP6V0E2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP biosynthetic process grouped by ATP6V0E2-low versus ATP6V0E2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0E2→partner) and Y-score (partner→ATP6V0E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	ATP biosynthetic process →	+0.119	+1.733	<.001	.003	2	12
UPPER_AERODIGESTIVE_TRACT	Purine nucleoside triphosphate biosynthetic process →	+0.106	+2.041	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Purine ribonucleoside triphosphate biosynthetic process →	+0.106	+2.041	<.001	<.001	3	11
LUNG_SCLC	Nucleoside triphosphate biosynthetic process →	+0.124	+0.921	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.122	+1.676	.001	.005	3	11
LUNG_NSCLC_LUSC	Methylglyoxal metabolic process →	+0.145	+1.654	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,025 associations by consensus.

ATP biosynthetic process by ATP6V0E2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →