ATP6V0E1

Across TCGA patient cohorts, ATP6V0E1 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V0E1-associated genes across cancer lineages are KRT17P1, MAGEA2B, and RN7SKP104. Each is linked with ATP6V0E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0E1-to-partner and partner-to-ATP6V0E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT17P1 grouped by ATP6V0E1-low versus ATP6V0E1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0E1→partner) and Y-score (partner→ATP6V0E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KRT17P1 →	+0.121	+3.542	.005	.004	3	1
UCEC	MAGEA2B →	+0.041	+3.621	.002	.003	3	1
UCEC	RN7SKP104 →	+0.065	+4.242	<.001	.006	3	1
UCEC	RNU6-662P →	+0.385	+3.299	<.001	.006	3	1
UCEC	TRAJ52 →	+0.771	+2.756	<.001	.006	3	1
UCEC	TRAJ5 →	+1.004	+3.095	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

KRT17P1 by ATP6V0E1 expression — UCEC

Explore this box plot interactively →