ATP6V0E1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP6V0E1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V0E1-associated genes across cancer lineages are Th2 cells and Plasma cells. Each is linked with ATP6V0E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0E1-to-partner and partner-to-ATP6V0E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by ATP6V0E1-low versus ATP6V0E1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0E1→partner) and Y-score (partner→ATP6V0E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTh2 cells →+0.291+2.815.005.03631
UCECPlasma cells →-0.025-2.957.046.03711
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Th2 cells by ATP6V0E1 expression — UCEC

Box plot of Th2 cells in ATP6V0E1-low vs ATP6V0E1-high samples in UCEC.

Explore this box plot interactively →

Exploration