ATP6V0E1

Across TCGA cell cohorts, ATP6V0E1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,771 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ATP6V0E1-associated GO terms across cancer lineages are Positive regulation of DNA-directed DNA polymerase activity, Protein targeting to vacuole involved in autophagy, and Sphingolipid catabolic process. Each is linked with ATP6V0E1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ATP6V0E1-to-partner and partner-to-ATP6V0E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA-directed DNA polymerase activity grouped by ATP6V0E1-low versus ATP6V0E1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0E1→partner) and Y-score (partner→ATP6V0E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of DNA-directed DNA polymerase activity →	-0.151	-0.871	<.001	<.001	3	13
LIVER	Protein targeting to vacuole involved in autophagy →	+0.217	+0.957	.001	.002	3	13
BONE	Sphingolipid catabolic process →	+0.126	+1.070	<.001	<.001	3	12
BONE	'de novo' IMP biosynthetic process →	-0.150	-1.057	.004	.006	2	12
CNS	Ribosomal protein import into nucleus →	-0.081	-1.005	<.001	.004	3	11
BLOOD_Myeloma	De novo centriole assembly →	-0.149	-0.888	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,771 associations by consensus.

Positive regulation of DNA-directed DNA polymerase activity by ATP6V0E1 expression — SOFT_TISSUE

Explore this box plot interactively →